🧫
DPYD polymorphisms association with fluoropyrimidine ADRs
active
experiment
Created: 2026-04-10T23:12:10
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-cc43e3c7-b8ae-4740-bddd-5
🧫 Experiment Protocol
Genetic Associationproposed
N = 1254
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T23:12:10.305778'} |
| p_value | 0.05 |
| protocol | Real-Time PCR analysis of DNA extracted from 3ml whole blood samples to genotype nine DPYD variants: c.496A>G, c.1236G>A/HapB3, c.1601G>A (DPYD*4), c.1627A>G (DPYD*5), c.1679T>G (DPYD*13), c.1896T>C, |
| effect_size | None |
| sample_size | 1254 |
| source_pmid | 30723313 |
| extracted_at | 2026-04-10T16:12:10.301968 |
| _schema_version | 1 |
| experiment_type | genetic_association |
| success_criteria | statistical significance (p < 0.05) for association between DPYD variants and ADRs |
| expected_outcomes | identification of DPYD variants significantly associated with fluoropyrimidine ADRs that could be used for pre-emptive screening |
| statistical_methods | univariate analysis |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
1
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.