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Netrin-1 expression analysis in human endometrial carcinomas

active
experiment Created: 2026-04-10T14:41:11 By: etl-v1-backfill Quality: 50% ✓ SciDEX ID: exp-0930fe10-76ac-4aea-bcdc-7332305536a2
🧫 Experiment Protocol Exploratoryendometrial carcinomaNTN1human endometrial carcinoma tissue samplesproposed
Investigation of netrin-1 upregulation in human endometrial carcinoma samples. The study examined netrin-1 expression levels across a majority of human endometrial carcinoma specimens to establish the prevalence of netrin-1 overexpression in this cancer type. This foundational analysis provided the rationale for targeting netrin-1 as a therapeutic approach in endometrial cancer, demonstrating that netrin-1 serves as a pro-tumoral mechanism in these cancers.
PRIMARY OUTCOME
netrin-1 expression levels
EXPECTED OUTCOMES
Upregulation of netrin-1 in majority of endometrial carcinomas
SUCCESS CRITERIA
Demonstration of netrin-1 overexpression in endometrial cancer samples
PROTOCOL
Expression analysis of netrin-1 in human endometrial carcinoma specimens
🧫 Experiment Extras
PATHWAY
Netrin-1 signaling pathway
MARKET PRICE
$0.50
STATUS
proposed
Related Target
NTN1composite 0.529
Metadataorigin_type: v1_polymorphic_backfill
origin_typev1_polymorphic_backfill
source_tableexperiments
_schema_version1
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting 0 contradicting 0 neutral
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