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Complement and microglia mediate early synapse loss in Alzheimer mouse models.
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📄 Paper Details
Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Hong S, Beja-Glasser VF, Nfonoyim BM, Frouin A, Li S, Ramakrishnan S, Merry KM, Shi Q, Rosenthal A, Barres BA
Abstract
1. Science. 2016 May 6;352(6286):712-716. doi: 10.1126/science.aad8373. Epub 2016 Mar 31. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Hong S(1), Beja-Glasser VF(#)(1), Nfonoyim BM(#)(1), Frouin A(1), Li S(2), Ramakrishnan S(1), Merry KM(1), Shi Q(2), Rosenthal A(3)(4)(5), Barres BA(6), Lemere CA(2), Selkoe DJ(2)(7), Stevens B(1)(8). Author information: (1)F.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, Massa...
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📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
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Incoming
1
Outgoing
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