📄
Expression of the lymphangiogenic reelin is associated with sex-dependent calcific aortic stenosis in men.
active
paper
Created:
By: unknown
Quality:
50%
✓ SciDEX
ID: paper-40188710
📄 Paper Details
Expression of the lymphangiogenic reelin is associated with sex-dependent calcific aortic stenosis in men.
["Jover E", "Garaikoetxea M", "Mart\u00edn-N\u00fa\u00f1ez E", "Go\u00f1i-Ol\u00f3riz M", "San-Ildefonso-Garc\u00eda S", "Navarro A", "Fern\u00e1ndez-Celis A", "\u00c1lvarez V", "S\u00e1daba R", "Calv
Abstract
BACKGROUND AND AIMS: Aortic stenosis is a major form of adult valvulopathy with strong sex-related phenotypes. Circulating reelin, a large extracellular glycoprotein, regulates lymphangiogenesis and inflammation and promotes atherosclerosis, a risk factor in aortic stenosis. We sought to investigate the sex-dependent expression of reelin in stenotic aortic valves to comprehend its role in aortic stenosis progression. METHODS: Reelin was studied in aortic valves and serum samples from severe aort...
▸Metadata
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
1
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.