📄
Investigating the Effect and Mechanism of Protocatechuic Aldehyde on Vascular Dementia Based on Multi-Omics Approach.
active
paper
Created:
By: unknown
Quality:
50%
✓ SciDEX
ID: paper-41897347
📄 Paper Details
Investigating the Effect and Mechanism of Protocatechuic Aldehyde on Vascular Dementia Based on Multi-Omics Approach.
["Xiao T", "Tao J", "Tan J", "Yi X", "Wang Z", "Duan X"]
Abstract
Background: The therapeutic effect and mechanism of protocatechuic aldehyde (PAL) on vascular dementia (VaD) were studied from a multi-group perspective. Methods: The pharmacological property of PAL was assessed by using both an in vivo two-vessel occlusion (2VO) rat model and an in vitro astrocyte-neuron co-culture system with oxygen-glucose deprivation (OGD) injury. On the basis of neurobehavioral test, Morris' water maze test and hematoxylin and eosin staining, the pathological transformation...
▸Metadata
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
1
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.