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🎯 Drug Targets

Browse 3 drug targets with druggability analysis, composite scores, and clinical context

3
Targets
0
High Druggability
0.65
Avg Score
15
Target Classes
Druggability Distribution
High: 0Medium: 0Low: 3Unknown: 0
Avg druggability score: 0.369
Clinical Pipeline
Approved: 0Phase III: 2Phase II: 0Phase I: 1Preclinical: 0
Total compounds: 5 · Approved: 0
Class All Classes Enzyme (35) Signaling Protein (25) Structural Protein (17) Protein (16) Gpcr (13) Ion Channel (12) Transcription Factor (11) Receptor (11) Ligand (10) Transporter (8) Epigenetic Regulator (8) Kinase (7) Protease (4) Other (4) Chaperone (4)
Druggability All Druggability Low (100) Medium (62) High (14) Undruggable (6) other (3)
Sort Score Druggability Gene A-Z Market Price
Filtered by: class=chaperone, druggability=Low — 3 results
HSP90AA1 Heat Shock Protein 90 Alpha Family Class A Member Phase 3
Chaperone Low Druggability
Score
0.70
Drug.
0.45
Safety
0.50
Drugs
2
Hyps
2
Papers
14
Small molecule inhibitor binding to ATP-binding pocket of chaperone
NPM1 Nucleophosmin Phase 3
Chaperone Low Druggability
Score
0.63
Drug.
0.30
Safety
0.30
Drugs
1
Hyps
1
Papers
30
Small molecule modulators of nucleolar function and protein interactions
DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 Phase 1
Chaperone Low Druggability
Score
0.60
Drug.
0.35
Safety
0.40
Drugs
2
Hyps
3
Papers
14
Allosteric modulation of protein-protein interactions with Hsp70
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