| Gene Symbol | ent-gene-ca639fc1 |
| Chromosome | 4q22.1 |
| Homodimeric architecture | Two ABCG2 monomers assemble via extensive TMD interactions to form a functional transporter with a central drug-binding cavity |
| Substrate specificity | Preferentially transports sulfated and glucuronidated conjugates, porphyrins, dietary flavonoids, urate, and various chemotherapeutic agents |
| Cooperative transport | Some substrates show positive cooperativity, with binding at one site enhancing transport at the other |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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