protein 3,049 words KG: AMYLOIDBETA 2026-03-23
kind:proteinsection:proteinsstate:published
Contents

Amyloid-Beta (Aβ)

🔬 Protein Info
Gene SymbolAPP
AliasesAMYLOIDBETA
Chromosome21
Protein FamilyAmyloid precursor protein family
Functionis a 40-42 amino acid peptide that plays a central role in the pathogenesis of Alzheimer's disease (AD) and related amyloidopathies[@hardy2002].
Primary ExpressionExtracellular, membrane-associated
Subcellular LocalizationExtracellular, membrane-associated
UniProt IDP05067
GeneCardsAPP
Human Protein AtlasAPP
GeneAPP
PDB1IYT, 1BA4, 2BEG, 5OQV
Mol. Weight4 kDa (Aβ40/42)
Associated DiseasesAlzheimer's Disease, Cerebral Amyloid Angiopathy
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph