gene 838 words KG: APOC3 2026-03-24
kind:genesection:genesstate:published
Contents

APOC3 Gene

🧬 Gene Info
Gene SymbolAPOC3
Full NameApolipoprotein C-III
AliasesApoC-III, APOC3
Chromosome11q23.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionHepatocytes in the liver (highest expression)
Molecular Weight8.8 kDa
Amino Acids79 aa
PathwaysCholesterol
NCBI Gene ID345
Ensembl IDENSG00000110245
GeneCardsAPOC3
Human Protein AtlasAPOC3
Therapy TypeExample
Antisense OligonucleotideVolanesorsen (ISIS 304801)
Associated DiseasesAging, Als, Atherosclerosis, Cardiovascular
InteractionsAPOA1, APOE, ABCA1, APOC1, ABCA2, APOC2
KG Connections100 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

APOC3 associated_with LDLR
APOC3 transports APOC2
APOC3 degrades APP
APOC3 degrades PSEN2
APOC3 activates APOA1
APOC3 degrades MAPT
APOC3 degrades SREBF1
APOC3 degrades NCSTN
APOC3 degrades PSEN1
APOC3 activates APOE