cell 753 words KG: ent-gene-73ebbe3d 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

ALDH1A1+ Dopamine Neurons

🔬 Protein Info
Gene Symbolent-gene-73ebbe3d
CategoryDopaminergic Neurons
LocationSubstantia nigra pars compacta, ventral tegmental area
Cell TypesALDH1A1+ dopamine neurons
Primary NeurotransmitterDopamine
Key MarkersALDH1A1, TH, PITX3, DAT
TaxonomyID
ConditionRelationship
Parkinson's DiseasePreferential loss of ALDH1A1+ neurons
Progressive Supranuclear PalsyVariable involvement
Multiple System AtrophyLess selective vulnerability
Dementia with Lewy BodiesLewy body pathology in ALDH1A1+ neurons
AgingGradual decline in ALDH1A1 expression
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.42
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38

Related Analyses (13)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between neurons and glia
neurodegeneration · archived

Knowledge Graph (2 edges)

ent-gene-73ebbe3d data_in benchmark_ot_ad_answer_key:ALDH1A1
benchmark_ot_ad_answer_key:ALDH1A1 data_in ent-gene-73ebbe3d