cell 561 words KG: ent-gene-f4a41ec1
Contents

Beclin-1 (BECN1) Neurons

🔬 Protein Info
Gene Symbolent-gene-f4a41ec1
Subcellular Localization**Neuronal soma**: Cytoplasmic, associated with endoplasmic reticulum
Cerebral cortexpyramidal neurons
HippocampusCA1/CA3 neurons
Substantia nigradopaminergic neurons
CerebellumPurkinje cells
Spinal cordmotor neurons
Neuronal somaCytoplasmic, associated with endoplasmic reticulum
Axon initial segmentLocal autophagy regulation
Synaptic terminalsPresynaptic autophagy
DendritesDistributed autophagy
Bcl-2/Beclin-1 complexRegulated by phosphorylation and ubiquitination
Ambra1Activates Beclin-1 during stress
RubiconNegative regulator of autophagy
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

APOE-Dependent Autophagy Restoration
Score: 0.84
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.66
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65

Related Analyses (12)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Knowledge Graph (2 edges)

ent-gene-f4a41ec1 data_in benchmark_ot_ad_answer_key:BECN1
benchmark_ot_ad_answer_key:BECN1 data_in ent-gene-f4a41ec1

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