cell 901 words KG: ent-gene-fc3f87ca 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

mGluR3 (GRM3) Neurons

🔬 Protein Info
Gene SymbolGRM3
Full NameGlutamate Metabotropic Receptor 3
Chromosome7q21.12
Protein FamilyClass C GPCR, mGluR family
Protein TypeReceptor
FunctionmGluR3 is a presynaptic autoreceptor and postsynaptic receptor that
Molecular Weight98 kDa
Amino Acids879 aa
PathwaysMAPK, PI3K, NF-κB
UniProt IDQ14832
NCBI Gene ID2915
Ensembl IDENSG00000138821
OMIM604099
GeneCardsGRM3
Human Protein AtlasGRM3
Associated DiseasesALS, Aging, Alzheimer, Bipolar, Depression
InteractionsGRM4, SYNGR1, GRIN2B, NCAM1, NRG1, RGS4
KG Connections128 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38

Related Analyses (12)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived

Knowledge Graph (2 edges)

ent-gene-fc3f87ca data_in benchmark_ot_ad_answer_key:GRM3
benchmark_ot_ad_answer_key:GRM3 data_in ent-gene-fc3f87ca