cell 566 words KG: ent-gene-3b7991c9 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

Nerve Growth Factor (NGF) Responsive Neurons

🔬 Protein Info
Gene SymbolNGF
Full NameNerve Growth Factor
Chromosome1p13.1
Protein FamilyNeurotrophin family
Primary ExpressionPrimarily in nociceptive sensory neurons, cholinergic basal forebrain neurons, sympathetic ganglia
Molecular Weight30 kDa
Amino Acids120 aa
Exons3
PathwaysPI3K, MAPK
UniProt IDP01138
NCBI Gene ID4800
Ensembl IDENSG00000111665
OMIM162030
GeneCardsNGF
Human Protein AtlasNGF
Associated DiseasesALS, ANGIOGENESIS, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Known Drugs/Compoundsaducanumab, lecanemab, metformin
InteractionsCHR2, BDNF, GAIN, DCX, HES1, NESTIN
KG Connections799 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38

Related Analyses (11)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between neurons and glia
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

Knowledge Graph (2 edges)

ent-gene-3b7991c9 data_in benchmark_ot_ad_answer_key:NGF
benchmark_ot_ad_answer_key:NGF data_in ent-gene-3b7991c9