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Clinical: Personalized Parkinson Project (NCT03364894)
clinical
2,872 words
KG: Personalized Parkinson Project (NCT03364894)
2026-03-28
kind:clinical-trial
section:clinical-trials
state:published
topic:parkinsons
topic:precision-medicine
topic:biomarkers
topic:observational
Contents
Personalized Parkinson Project (NCT03364894)
Knowledge Graph
Related Hypotheses (26)
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.68
Multi-Modal Stress Response Harmonization
Score: 0.60
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.59
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57
Circadian Clock-Autophagy Synchronization
Score: 0.55
Circadian Glymphatic Rescue Therapy (Melatonin-focused)
Score: 0.55
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Vagal Afferent Microbial Signal Modulation
Score: 0.52
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.50
Lysosomal Calcium Channel Modulation Therapy
Score: 0.49
RNA Granule Nucleation Site Modulation
Score: 0.48
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.48
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.47
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46
HDAC3-Selective Inhibition for Clock Reset
Score: 0.46
Hypocretin-Neurogenesis Coupling Therapy
Score: 0.45
Cross-Seeding Prevention Strategy
Score: 0.45
Axonal RNA Transport Reconstitution
Score: 0.45
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.44
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.41
Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.39
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.38
Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Show 21 more
Related Analyses (21)
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
CRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed
Show 16 more
Related Experiments (4)
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
LRRK2/GBA Mutation Carrier Resilience — Why Some Carriers Ne
validation · proposed · Score: 0.40
Experiment: Multi-Ethnic PD GWAS
clinical · proposed · Score: 0.40
Knowledge Graph (1 edges)
Personalized Parkinson Project (NCT03364894)
references
SNCA