| Loss of finger dexterity | Inability to perform rapid, alternating finger movements (e.g., finger tapping) |
| Impaired manipulation | Difficulty with tasks requiring fine object manipulation (buttoning, writing, using utensils) |
| Clumsiness | Incoordination disproportionate to weakness |
| Asymmetric presentation | Almost always affects one hand (contralateral to affected hemisphere)[^4] |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
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