| Speech Rate | Slow, hesitant speech with frequent pauses |
| Phonology | Generally preserved, though sound errors may occur under stress |
| Comprehension | Relatively preserved for single words and simple sentences |
| Naming | Severe anomia, particularly for low-frequency words |
| Reading/Writing | Similar patterns to spoken language, with impaired naming and reading comprehension |
| Inferior Parietal Lobule (IPL) | Involved in semantic and phonological aspects of language |
| Angular Gyrus | Integrates sensory information and supports lexical-semantic processing |
| Posterior Temporal-Parietal Junction | Critical for sentence-level processing and repetition |
| CSF Biomarkers | Reduced amyloid-beta 42, elevated tau and phosphorylated tau |
| PET Imaging | Positive amyloid PET scans in most cases |
| Structural MRI | Characteristic pattern of left posterior temporal-parietal atrophy |
| Databases | OMIMOrphanetClinicalTrialsPubMed |