| Mean age of symptom onset | approximately 63 years (range 50-75), with diagnosis typically occurring at ~67 years |
| Sex distribution | Slight female predominance (~55:45), consistent with the higher female prevalence of AD overall |
| Disease duration | Mean survival approximately 7-8 years from symptom onset |
| Cerebral amyloid angiopathy | Present in most cases with AD pathology |
| Left temporoparietal junction | The region where temporal and parietal lobes meet, critical for phonological processing |
| Left posterior superior temporal gyrus | Involved in phonological representations |
| Left posterior perisylvian cortex | The language processing region surrounding the Sylvian fissure |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
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