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disease 1,990 words KG: synaptic_dysfunction 2026-03-24
kind:diseasesection:diseasesstate:published
Contents

Synaptic Dysfunction in 4R-Tauopathies Comparison

Disease Info
Associated Genesprotein_oligomers
KG Connections2 knowledge graph edges
DatabasesOMIMOrphanetClinicalTrialsPubMed

Knowledge Graph

Related Hypotheses (9)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68APOE-Dependent Autophagy Restoration
Score: 0.61Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.49Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.45

Related Analyses (12)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archivedSleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archivedSynaptic pruning by microglia in early AD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (3)

C3 — Complement Component 3
gene · KG edge: causesNeurodegeneration
disease · KG edge: contributes_toCA2 Pyramidal Neurons
cell · KG edge: causes

Knowledge Graph (2 edges)

synaptic_dysfunction contributes_to neurodegeneration
protein_oligomers causes synaptic_dysfunction
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