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Home / Wiki / Event: AAIC 2026: Synaptic Dysfunction and Neural Circuit Alteratio

event 2,393 words KG: Biomarker 2026-03-30

kind:event section:events state:published

Contents

AAIC 2026: Synaptic Dysfunction and Neural Circuit Alterations

Knowledge Graph

Related Hypotheses (11)

Purinergic Signaling Polarization Control
Score: 0.55 Mechanosensitive Ion Channel Reprogramming
Score: 0.51 Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46 Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68 Prefrontal sensory gating circuit restoration via PV interne
Score: 0.59

Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.49 Metabolic Circuit Breaker via Lipid Droplet Modulation
Score: 0.48 Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.42 TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.41 Synaptic Vesicle Tau Capture Inhibition
Score: 0.34 Trans-Synaptic Adhesion Molecule Modulation
Score: 0.34

Related Analyses (10)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived Synaptic pruning by microglia in early AD
neurodegeneration · archived Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · failed Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · completed Synaptic pruning by microglia in early AD
neurodegeneration · completed

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40 Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (15)

ALS Therapeutic Landscape — Programs by Phase and Modal
disease · Pages share 3 hypotheses Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 3 hypotheses VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 3 hypotheses

Vagus Nerve Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses Ubiquitin-Proteasome System Dysfunction in Neurodegener
mechanism · Pages share 3 hypotheses ubiquitin-proteasome-dysfunction-neurodegeneration
mechanism · Pages share 3 hypotheses Transdiagnostic Proteomic Changes in Neurodegeneration
mechanism · Pages share 3 hypotheses Transdiagnostic Proteomic Changes in Neurodegeneration
mechanism · Pages share 3 hypotheses Therapeutic Targets in Neurodegeneration
mechanism · Pages share 3 hypotheses Tertiary Lymphoid Organs in Neurodegeneration
mechanism · Pages share 3 hypotheses TBK1 Autophagy and Neuroinflammation ALS/FTD Causal Cha
mechanism · Pages share 3 hypotheses Tau Seeding and Propagation Pathway
mechanism · Pages share 3 hypotheses T-Cell Dysfunction in Neurodegeneration
mechanism · Pages share 3 hypotheses

Knowledge Graph (11 edges)

Biomarker biomarker_for Thyroid Cancer

Biomarker correlates_with Disease Trajectory

Biomarker biomarker_for Septic Shock

Biomarker involved_in Sepsis Diagnosis

Biomarker biomarker_for Prostate Cancer

Biomarker biomarker_for Aging

Biomarker biomarker_for Amyotrophic Lateral Sclerosis

Biomarker biomarker_for Frontotemporal Dementia

Biomarker biomarker_for Alzheimer's Disease

HMGB1 biomarker_for Biomarker

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