gene 730 words KG: AOX1 2026-03-24
kind:genesection:genesstate:published
Contents

AOX1 - Aldehyde Oxidase 1

🧬 Gene Info
Gene SymbolAOX1
Full NameAldehyde Oxidase 1
AliasesPage for AOX1
Chromosome2q33
FunctionAOX1 encodes aldehyde oxidase, a homodimeric enzyme that catalyzes the oxidation of aldehydes into carboxylic acids.
Primary Expressionmotor neurons and may contribute to oxidative stress in ALS
UniProt IDQ06278
NCBI Gene ID303
Ensembl IDENSG00000138382
GeneCardsAOX1
Human Protein AtlasAOX1
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (1)

Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.51

Related Analyses (2)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (2 edges)

AOX1 data_in benchmark_ot_ad_answer_key:AOX1
benchmark_ot_ad_answer_key:AOX1 data_in AOX1