gene 621 words KG: ARSB
Contents

ARSB Gene

🧬 Gene Info
Gene SymbolARSB
Full NameArylsulfatase B
Chromosome5q14.1
Protein TypeHydrolase
FunctionArylsulfatase B is a member of the sulfatase family of enzymes.
Primary Expressionvarious tissues including brain - Higher expression in liver and skeletal muscle - Lysosomal enzymes generally expressed in [neurons](/entities/neuron
Molecular Weight56 kDa
UniProt IDP15884
Ensembl IDENSG00000113273
GeneCardsARSB
Human Protein AtlasARSB
Lysosomal FunctionEssential for normal catabolism of dermatan sulfate and chondroitin sulfate
Proteoglycan TurnoverRegulates the degradation and recycling of proteoglycans in the extracellular matrix
Cell SignalingProper GAG metabolism influences cell growth, migration, and signaling
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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