gene 670 words KG: ASAP1 2026-03-22
kind:genesection:genesstate:published
Contents

ASAP1 Gene

🧬 Gene Info
Gene SymbolASAP1
Full NameArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1
Chromosome9q34.3
FunctionASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1), also known as DDEF1 or AGAP2, is a member of the ArfGAP (ADP-ribosylation factor GTPase-activating protein) family.
Primary Expressionvarious cancers, making it a dual therapeutic target
UniProt ID[Q9ULH0](https://www.uniprot.org/uniprot/Q9ULH0)
Ensembl IDENSG00000153317
OMIM611752
GeneCardsASAP1
Human Protein AtlasASAP1
SH3 domainProline-rich motif interactions
Ankyrin repeatsProtein scaffolding
PH domainPhosphoinositide binding
ArfGAP domainGTPase activity
BrainParticularly in regions affected in neurodegeneration
Associated DiseasesAlzheimer's Disease (AD
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph