gene 3,224 words KG: BAG5 2026-03-29
kind:genesection:entitiesstate:publishedtopic:parkinsons
Contents

BAG5 Gene

🧬 Gene Info
Gene SymbolBAG5
Full NameBCL2-Associated Athanogene 5
Chromosome14q32.33
Protein FamilyBAG family, Hsp70 co-chaperones
Protein TypeChaperone
Functionis a multi-domain co-chaperone protein that plays critical roles in neuronal survival, protein quality control, mitochondrial dynamics, and autophagy regulation.
Primary Expressionvulnerable neuronal populations including dopaminergic neurons of the substantia nigra pars compacta, cortical neurons, hippocampal neurons, and cereb
Subcellular Localization, including nuclear localization signals and mitochondrial targeting sequences. This enables BAG5 to function in multipl
Molecular Weight49 kDa
Amino Acids446 aa
Exons17
UniProt ID[Q9NS69](https://www.uniprot.org/uniprot/Q9NS69)
Ensembl IDENSG00000164478
GeneCardsBAG5
Human Protein AtlasBAG5
Associated DiseasesParkinson's disease
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph