gene 1,590 words KG: CACNG1 2026-03-29
kind:genesection:genesstate:published
Contents

CACNG1 Gene - Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 1

🧬 Gene Info
Gene SymbolCACNG1
AliasesPage for CACNG1 Protein
Chromosome17q24
FunctionCacng1 Protein Calcium Channel Gamma 1 Subunit is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, ...
Molecular Weight33 kDa
Amino Acids270 aa
Ensembl IDENSG00000096433
GeneCardsCACNG1
Human Protein AtlasCACNG1
First transmembrane domain (TM1)Contributes to channel subunit interaction interface
Second transmembrane domain (TM2)Forms the core of the channel pore (with gamma-1 specifically)
Third transmembrane domain (TM3)Involves subunit-subunit contacts
Fourth transmembrane domain (TM4)Participates in membrane-spanning region
Loop regionsMajor extracellular loop between TM1 and TM2 contains N-linked glycosylation sites
C-terminal tailIntracellular domain involved in protein-protein interactions and modulation
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (19)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51

Related Analyses (7)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in