gene 2,574 words KG: CDR1 2026-03-28
kind:genesection:genesstate:published
Contents

CDR1 Gene

🧬 Gene Info
Gene SymbolCDR1
Full NameCerebellar Degeneration-Related Protein 1 (CDR1AS)
ChromosomeXq27.1
Functionis a stable circular RNA molecule that lacks the 5' cap and 3' polyadenylated tail typical of most coding transcripts.
UniProt IDQ9UIU7
Ensembl IDENSG00000283757
GeneCardsCDR1
Human Protein AtlasCDR1
BACE1The β-secretase enzyme that cleaves amyloid precursor protein (APP) to produce amyloid-beta peptides. Increased BACE1 activity promotes amyloid production, a hallmark of AD pathogenesis.
SNCAα-Synuclein, the protein that forms Lewy bodies in PD. Proper regulation of SNCA expression is critical, as overexpression can lead to aggregation and toxicity.
UCHL1Ubiquitin carboxy-terminal hydrolase L1, an enzyme important for protein degradation. Loss of UCHL1 function contributes to protein aggregation.
Associated Diseasesneurodegeneration
KG Connections2 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph