gene 1,332 words KG: CHCHD9 2026-03-28
kind:genesection:genesstate:published
Contents

CHCHD9 — Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 9

🧬 Gene Info
Gene SymbolCHCHD9
Full NameCoiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 9
Chromosome9q34.11
Protein TypeMitochondrial CHCHD family
Functionis a nuclear-encoded mitochondrial protein that plays critical roles in mitochondrial function, oxidative phosphorylation, and cellular stress response.
Primary ExpressionBrain (cerebral cortex, cerebellum), heart, skeletal muscle
UniProt IDQ8N5L4
NCBI Gene ID55033
Ensembl IDENSG00000177303
OMIM614295
GeneCardsCHCHD9
Human Protein AtlasCHCHD9
Protein ClassMitochondrial CHCHD family
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (19)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.61
PARP1 Inhibition Therapy
Score: 0.58
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
Senescent Cell Mitochondrial DNA Release
Score: 0.54

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed

Related Experiments (3)

Epigenetic Dysregulation in Huntington's Disease — Therapeut
validation · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
Microglial Contributions to Huntington's Disease Pathogenesi
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in