| Gene Symbol | CHRNB1 |
| Aliases | Cholinergic Receptor Nicotinic Beta Subunit 1 |
| Chromosome | 17p13.1 |
| Protein Family | Cys-loop receptor superfamily |
| Function | Ligand-gated ion channel mediating fast synaptic transmission |
| Primary Expression | select brain regions including basal forebrain, hippocampus, and cortex[@counts2021] |
| GeneCards | CHRNB1 |
| Human Protein Atlas | CHRNB1 |
| Stoichiometry | α1₂β1δγ(ε) |
| Location | Motor endplates, autonomic ganglia, some CNS neurons |
| Ion flux | Permeable to Na⁺ and K⁺ (and Ca²⁺ to a lesser degree) |
| Fast synaptic transmission | Response latency of <1 ms |
| Desensitization | Prolonged agonist exposure leads to receptor inactivation |
| Allosteric modulation | Multiple binding sites for modulatory compounds |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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