| Gene Symbol | CMYA5 |
| Chromosome | 5q32 |
| Protein Type | Gene |
| Function | is a gene that has attracted significant interest in neurodegeneration research. |
| Primary Expression | brain tissue, particularly in regions affected by Huntington's disease pathology such as the striatum and cortex |
| Subcellular Localization | Cytoplasmic with association to cytoskeletal elements |
| GeneCards | CMYA5 |
| Human Protein Atlas | CMYA5 |
| Multiple coiled-coil domains | Mediate protein-protein interactions |
| Proline-rich regions | Potential SH3 domain binding sites |
| Phosphorylation sites | Multiple serine/threonine residues for regulatory modification |
| Subcellular localization | Cytoplasmic with association to cytoskeletal elements |
| Striatum | High expression in medium spiny neurons, the cell type most vulnerable in HD |
| Cortex | Moderate expression across cortical layers |
| Hippocampus | Expression in pyramidal neurons |
| Associated Diseases | Huntington's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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