gene 798 words KG: COQ2
Contents

COQ2 Gene - Coenzyme Q Biosynthesis Protein COQ2

🧬 Gene Info
Gene SymbolCOQ2
Full NameCoenzyme Q Biosynthesis Protein COQ2
AliasesCoQ10
Chromosome4q22.1
Protein TypeEnzyme
Functionis a mitochondrial enzyme that catalyzes the rate-limiting step in coenzyme Q (CoQ10, ubiquinone) biosynthesis.
Molecular Weight20 kDa
Amino Acids421 aa
GeneCardsCOQ2
Human Protein AtlasCOQ2
COQ4Complex scaffold
COQ6Hydroxylase
COQ7Hydroxylase (COQ7 is also called COQ5 in some organisms)
COQ8A/COQ8BKinases
COQ9Lipid-binding chaperone
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (15)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
CYP46A1 Overexpression Gene Therapy
Score: 0.77
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
APOE Isoform Conversion Therapy
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56

Related Analyses (8)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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