gene 1,879 words KG: DLX6
Contents

DLX6 — Distal-Less Homeobox 6

🧬 Gene Info
Gene SymbolDLX6
Full NameDistal-Less Homeobox 6
Chromosome7q21.3
Protein TypeTranscription Factor
Functionis a member of the DLX family of homeobox transcription factors that play critical roles in embryonic brain development, particularly in the formation of GABAergic neurons in the forebrain.
Primary Expressionthe olfactory bulb, linking it to olfactory dysfunction common in neurodegenerative diseases:
Amino Acids326 aa
UniProt ID[O43516](https://www.uniprot.org/uniprot/O43516)
Ensembl IDENSG00000106483
GeneCardsDLX6
Human Protein AtlasDLX6
Homeodomain binding sitesTAAT motif recognition for DNA binding
Enhancer elementsRemote enhancers controlling spatiotemporal expression
Conserved non-coding sequencesDLX5/6 ultraconserved elements with regulatory function
Embyronic day 10.5-18.5High expression in ventral telencephalon
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph