| Gene Symbol | GARS1 |
| Aliases | Glycyl-tRNA synthetase 1 |
| Protein Type | Synthetase |
| Function | The enzymatic reaction proceeds through a two-step mechanism |
| Ensembl ID | ENSG00000106105 |
| GeneCards | GARS1 |
| Human Protein Atlas | GARS1 |
| N-terminal domain | Involved in dimerization and protein-protein interactions |
| Catalytic domain | Contains the active site for amino acid activation and tRNA binding |
| C-terminal domain | Contributes to tRNA recognition and editing function |
| Editing domain | Prevents mischarging of tRNA with incorrect amino acids (proofreading) |
| RNA splicing | Associates with spliceosome components |
| Cell signaling | Modulates MAPK/ERK and PI3K/AKT pathways |
| Immune regulation | Involved in interferon-responsive gene expression |
| Angiogenesis | Promotes blood vessel formation through VEGF signaling |
| Associated Diseases | neurodegeneration |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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