gene 1,493 words KG: GRIP3 2026-03-27
kind:genesection:genesstate:published
Contents

GRIP3 (Glutamate Receptor Interacting Protein 3)

🧬 Gene Info
Gene SymbolGRIP3
Full NameGlutamate Receptor Interacting Protein 3
ChromosomeXq28
Protein TypeScaffold Protein
Functionis a member of the GRIP family of PDZ domain-containing scaffold proteins that play critical roles in synaptic organization, glutamate receptor trafficking, and neuronal signaling.
Primary Expressionspecific brain regions where it contributes to synaptic plasticity and neuronal function
Subcellular Localizationpostsynaptic compartments, where it associates with excitatory synapses using glutamate as the neurotransmitter
Molecular Weight116 kDa
Amino Acids063 aa
UniProt IDQ9N2L8
NCBI Gene ID10054
Ensembl IDENSG00000155906
GeneCardsGRIP3
Human Protein AtlasGRIP3
Ionotropic glutamate receptorsGRIP3 may influence NMDA receptor function indirectly through interactions with associated proteins
Associated DiseasesAlzheimer's Disease, Intellectual Disability, Neurodevelopmental Disorders
DatabasesGeneCardsHPASTRING

Knowledge Graph