gene 1,463 words KG: LDLRAP1
Contents

LDLRAP1 — Low Density Lipoprotein Receptor Adaptor Protein 1

🧬 Gene Info
Gene SymbolLDLRAP1
Full NameLow Density Lipoprotein Receptor Adaptor Protein 1
Chromosome1p36
Protein TypeAdaptor Protein
Functionis an adaptor protein essential for LDL receptor function.
Primary Expressionmost tissues including the brain
Molecular Weight35 kDa
Amino Acids306 aa
Exons9
UniProt ID[Q4ZHG4](https://www.uniprot.org/uniprot/Q4ZHG4)
Ensembl IDENSG00000157911
OMIM603751
GeneCardsLDLRAP1
Human Protein AtlasLDLRAP1
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (14)

Cholesterol-CRISPR Convergence Therapy for Neurodegeneration
Score: 0.48
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.53
Membrane Cholesterol Gradient Modulators
Score: 0.52
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51

Related Analyses (4)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
CRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (3)

AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40
AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40
Sex Differences in Alzheimer's Disease — mechanisms and ther
clinical · proposed · Score: 0.40

See Also (15)

Extracellular Vesicle and Tunneling Nanotube-Mediated S
mechanism · Pages share 6 hypotheses
Neurodegeneration
disease · KG edge: implicated_in
Senescent Cell Clearance in Neurodegeneration
mechanism · Pages share 5 hypotheses
RNA-Targeted Therapies in Neurodegeneration
mechanism · Pages share 5 hypotheses
PPAR Signaling Pathway in Neurodegeneration
mechanism · Pages share 5 hypotheses