| Gene Symbol | LIG4 |
| Full Name | DNA Ligase 4 |
| Chromosome | 13q33.3 |
| Protein Type | Enzyme |
| Function | The NHEJ pathway operates throughout the cell cycle and does not require sequence homology, making it essential for genomic stability. |
| Primary Expression | all tissues, including high expression in: |
| UniProt ID | [P18859](https://www.uniprot.org/uniprot/P18859) |
| Ensembl ID | ENSG00000174444 |
| GeneCards | LIG4 |
| Human Protein Atlas | LIG4 |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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