gene 685 words KG: MBD3 2026-03-24
kind:genesection:genesstate:published
Contents

MBD3 Gene - Methyl-CpG Binding Domain Protein 3

🧬 Gene Info
Gene SymbolMBD3
AliasesMBD3A, NURD
Chromosome19p13.3
FunctionMBD3 is a core component of the NuRD complex, which possesses both chromatin remodeling ATPase (CHD4/Mi-2) and histone deacetylase (HDAC1/2) activities.
UniProt IDQ9UBB4
NCBI Gene ID53615
Ensembl IDENSG00000071655
OMIM157574
GeneCardsMBD3
Human Protein AtlasMBD3
Gene NameMethyl-CpG Binding Domain Protein 3
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (13)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56

Related Analyses (11)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in