gene 873 words KG: MBD4 2026-03-21
kind:genesection:genesstate:published
Contents

MBD4 Gene - Methyl-CpG Binding Domain Protein 4

🧬 Gene Info
Gene SymbolMBD4
Full NameMBD4 - Methyl-CpG Binding Domain Protein 4
AliasesPage for MBD4 Gene, Page for MBD4 Protein
Chromosome18q21.2.
Protein TypeGene
Functionis a DNA repair enzyme encoded by the MBD4 gene located on chromosome 18q21.
Primary Expressionmost human tissues with particular significance in: - Brain (neurons, astrocytes, microglia) - Hematopoietic system - Gastroin
Amino Acids606 aa
Exons16
NCBI Gene IDSearch NCBI
GeneCardsMBD4
Human Protein AtlasMBD4
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (10)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.59
CYP46A1 Overexpression Gene Therapy
Score: 0.86
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72

Related Analyses (11)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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