gene 1,779 words KG: MGEA5
kind:genesection:genesstate:publishedtopic:psptopic:cbstopic:alzheimers
Contents

MGEA5 — O-GlcNAcase (OGA)

🧬 Gene Info
Gene SymbolMGEA5
Full NameMeningioma Expressed Antigen 5 (N-acetylneuraminidase)
AliasesGene profile: MGEA5
Chromosome10q24.32
FunctionMGEA5 encodes O-GlcNAcase (OGA), a glycoside hydrolase that catalyzes the removal of O-linked β-N-acetylglucosamine (O-GlcNAc) from serine and threonine residues on target proteins.
Molecular Weight~103 kDa
Amino Acids917 aa
UniProt IDQ9H3K2
GeneCardsMGEA5
Human Protein AtlasMGEA5
Protein ProductO-GlcNAcase (OGA)
EC Number3.2.1.96
Alternative NamesOGA, MGEA5, NCOAT (Nuclear Cytoplasmic O-GlcNAcase and Transcriptional coactivator)
Protein Length917 amino acids
CompoundCompany
Associated DiseasesAlzheimer's disease
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph