gene 3,956 words KG: NDUFAF3 2026-03-26
kind:genesection:genesstate:published
Contents

NDUFAF3 Gene

🧬 Gene Info
Gene SymbolNDUFAF3
Full NameNADH Dehydrogenase Complex Assembly Factor 3
Chromosome3p21.31
Functionencodes a critical mitochondrial assembly factor required for the proper assembly and function of complex I (NADH:ubiquinone oxidoreductase) of the mitochondrial electron transport chain[@saada2009...
Primary ExpressionHigh in brain, heart, muscle (high energy tissues)
Molecular Weight22 kDa
Amino Acids198 aa
UniProt ID[Q9P0U4](https://www.uniprot.org/uniprot/Q9P0U4)
Ensembl IDENSG00000163293
OMIM618196
GeneCardsNDUFAF3
Human Protein AtlasNDUFAF3
Associated Diseasesneurodegeneration
KG Connections5 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (16)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Digital Twin-Guided Metabolic Reprogramming
Score: 0.61
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.48

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (5 edges)

NDUFAF3 associated_with RHOH
NDUFAF3 associated_with CDK10
NDUFAF3 associated_with MC1R
NDUFAF3 associated_with ERBB3
GTPBP3 associated_with NDUFAF3