gene 1,091 words KG: NPAS1 2026-03-21
kind:genesection:genesstate:published
Contents

NPAS1 - Neuronal PAS Domain Protein 1

🧬 Gene Info
Gene SymbolNPAS1
Full NameNeuronal PAS Domain Protein 1
AliasesPage for NPAS1
Chromosome19q13.12
Protein TypeTranscription Factor
Functionencodes a neuronal transcription factor of the bHLH-PAS (basic Helix-Loop-Helix-Per-ARNT-Sim) family, involved in circadian rhythm regulation, brain development, and cellular stress responses.
Primary Expressionmotor neurons and may regulate genes important for their survival
GeneCardsNPAS1
Human Protein AtlasNPAS1
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (18)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Circadian-Synchronized Proteostasis Enhancement
Score: 0.58
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.56

Related Analyses (9)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in