gene 577 words KG: NRP2 2026-03-21
kind:genesection:genesstate:published
Contents

NRP2 Gene

🧬 Gene Info
Gene SymbolNRP2
FunctionNRP2 participates in multiple signaling pathways:
GeneCardsNRP2
Human Protein AtlasNRP2
Axon GuidanceNRP2 serves as a receptor for class 3 semaphorins (SEMA3B, SEMA3F), directing axon migration
Dendritic MorphogenesisRegulates dendritic arborization
Synapse FormationInvolved in inhibitory synapse development
Neural Crest Cell MigrationCritical for peripheral nervous system development
AngiogenesisNRP2 acts as VEGF receptor, supporting blood vessel formation
LymphangiogenesisParticularly important for lymphatic vessel development
Vascular PatterningGuides developing blood and lymphatic vessels
Substantia NigraDopaminergic neurons
Peripheral Nervous SystemEnteric neurons, sensory ganglia
Endothelial CellsLymphatic and vascular endothelium
Neural Crest DerivativesSchwann cells, melanocytes
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph