| Gene Symbol | REEP1 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 22 kDa |
| Amino Acids | 199 aa |
| Pathways | PI3K/Akt pathway |
| Ensembl ID | ENSG00000068615 |
| GeneCards | REEP1 |
| Human Protein Atlas | REEP1 |
| Mitochondrial Cristae Structure | Shapes mitochondrial cristae and maintains cristae junctions essential for optimal oxidative phosphorylation |
| Axonal Mitochondria Distribution | Critical for proper distribution and anchoring of mitochondria in axons, particularly at synaptic terminals |
| ER-Mitochondria Contacts | Regulates membrane contact sites (MCS) between endoplasmic reticulum and mitochondria for calcium exchange and lipid transfer |
| Axonal Transport | Works with microtubule motors (kinesin/dynein) for organelle trafficking along axons |
| Mitochondrial Protein Import | Facilitates import of proteins into the mitochondrial matrix |
| Brain | Cerebral cortex, hippocampus, basal ganglia, and Purkinje cells of cerebellum |
| Spinal Cord | Motor neurons in the ventral horn |
| Associated Diseases | muscular_dystrophy, white_matter_damage |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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