gene 2,999 words KG: RPL10A
Contents

RPL10A — Ribosomal Protein L10A

🧬 Gene Info
Gene SymbolRPL10A
Full NameRibosomal Protein L10A
Chromosome6p21.3
Protein FamilyRibosomal protein L10 family
Functionencodes a protein of 216 amino acids that is highly conserved across eukaryotes, from yeast to humans [@rpla].
Primary ExpressionUbiquitous, high in brain and liver
Molecular Weight24 kDa
Amino Acids216 aa
Exons7
UniProt IDP62906
NCBI Gene ID6146
GeneCardsRPL10A
Human Protein AtlasRPL10A
N-terminal domainInvolved in binding to the 28S rRNA of the 60S subunit
Central domainContains the peptidyl transferase center interaction site
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (13)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
Epigenetic Memory Erasure via TET2 Activation
Score: 0.74
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.71
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
APOE-Dependent Autophagy Restoration
Score: 0.89
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
RNA Granule Nucleation Site Modulation
Score: 0.66
Arginine Methylation Enhancement Therapy
Score: 0.65
Nucleolar Stress Response Normalization
Score: 0.65

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

Anti-Tau Therapy Failure Mechanism in PSP — Why Clinical Tri
clinical · proposed · Score: 0.40
Brainstem Circuit Modulation for PSP
clinical · proposed · Score: 0.40
Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT
validation · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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