| Gene Symbol | SEPTIN5 |
| Full Name | Septin 5 |
| Chromosome | 22q11.21 |
| Function | encodes a member of the septin family of GTP-binding proteins essential for cytoskeleton organization, cell division, and membrane dynamics. |
| Primary Expression | the nervous system and is particularly important for synaptic vesicle organization, neurotransmitter release, and neuronal survival |
| Amino Acids | 367 aa |
| UniProt ID | Q9NSC5 |
| NCBI Gene ID | 54148 |
| Ensembl ID | ENSG00000100338 |
| GeneCards | SEPTIN5 |
| Human Protein Atlas | SEPTIN5 |
| Septin unique element (SUE) | a conserved 30-amino acid insert unique to septins |
| Cerebral cortex | Layer V pyramidal neurons (corticospinal motor neurons) |
| Hippocampus | CA3 pyramidal cells and dentate gyrus granule cells |
| Cerebellum | Purkinje cells (major inhibitory output neurons) |
| Associated Diseases | Parkinson's Disease, Alzheimer's Disease, Lewy Body Dementia |
| Databases | GeneCardsHPASTRING |
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