gene 1,687 words KG: SLC4A1 2026-03-26
kind:genesection:genesstate:published
Contents

SLC4A1 — Solute Carrier Family 4 Member 1 (Anion Exchanger 1)

🧬 Gene Info
Gene SymbolSLC4A1
Full NameSolute Carrier Family 4 Member 1 (Anion Exchanger 1)
AliasesAnion Exchanger 1
Chromosome17q21.31
Functionis a membrane protein that facilitates the exchange of chloride (Cl⁻) and bicarbonate (HCO₃⁻) ions across cell membranes[@alper2001].
Primary Expressionerythrocytes (red blood cells) and the kidney[@cordat2020], where it plays critical roles in ion homeostasis and cellular function
Molecular Weight95 kDa
Amino Acids911 aa
Exons26
GeneCardsSLC4A1
Human Protein AtlasSLC4A1
AnkyrinDirect binding
Protein 4.2Direct binding
SpectrinIndirect
Carbonic anhydrase IIFunctional coupling
Associated Diseasesneurodegeneration
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph