gene 2,026 words KG: SLIT2 2026-03-26
kind:genesection:genesstate:published
Contents

SLIT2 — Slit Guidance Ligand 2

🧬 Gene Info
Gene SymbolSLIT2
Full NameSlit Guidance Ligand 2
Chromosome4p15.1
Functionis a secreted protein that functions as the ligand for Roundabout (ROBO) receptors, mediating repulsive axon guidance and cell migration during development.
Primary Expressionhippocampal neurons
Amino Acids1529 aa
Exons36
GeneCardsSLIT2
Human Protein AtlasSLIT2
LRR flaking regionsVariable
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

Purinergic Signaling Polarization Control
Score: 0.55
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46

Related Analyses (2)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (15)

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mechanism · Pages share 3 hypotheses