| Gene Symbol | SV2C |
| Full Name | Synaptic Vesicle Glycoprotein 2C |
| Chromosome | 5q13.2 |
| Function | The SV2C gene encodes Synaptic Vesicle Glycoprotein 2C, a member of the SV2 family of proteins that are essential components of synaptic vesicles. |
| Primary Expression | various regions including the basal ganglia, cortex, hippocampus, and cerebellum |
| Molecular Weight | 82 kDa |
| Amino Acids | 200 aa |
| UniProt ID | Q9H0Y9 |
| NCBI Gene ID | 22983 |
| Ensembl ID | ENSG00000170873 |
| OMIM | 610516 |
| GeneCards | SV2C |
| Human Protein Atlas | SV2C |
| GWAS associations | Multiple studies have identified SV2C variants (rs1871678, rs6474359) as risk factors for sporadic PD |
| Mechanism | SV2C modulates synaptic vesicle filling and priming, affecting dopamine release capacity |
| Associated Diseases | Parkinson's disease |
| Databases | GeneCardsHPASTRING |
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