gene 943 words KG: TECPR2
Contents

Tectonin Beta-Propeller Repeat Containing 2

🧬 Gene Info
Gene SymbolTECPR2
Full NameTectonin Beta-Propeller Repeat Containing 2
Chromosome14q31.3
Protein TypeReceptor
FunctionIt plays critical roles in ciliary signaling, neuronal migration, and synaptic function.
Primary Expressionregions affected in Parkinson disease
UniProt IDQ9Y5P9
NCBI Gene ID1615
Ensembl IDENSG00000167962
OMIM615730
GeneCardsTECPR2
Human Protein AtlasTECPR2
AHI1Expressed in fetal and adult brain, with highest expression in cerebellum, basal ganglia, and hippocampus. Also expressed in kidney and testis. 6
GAD1Broad expression in GABAergic neurons throughout the brain, including cortex, hippocampus, basal ganglia, and cerebellum. More abundant than GAD2 in most brain regions. 7
GAD2Expressed in GABAergic neurons with synaptic localization. Higher expression in hippocampus and cerebellum compared to GAD1 in some regions. 8
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (26)

Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
Vocal Cord Neuroplasticity Stimulation
Score: 0.52
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
APOE-Dependent Autophagy Restoration
Score: 0.89
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
← Prevpg 2/2

Related Analyses (22)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.