Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LR.LOXL3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | LR.LOXL3 |
| Key Genes/Proteins | LOXL3, AND, LOX/LOXL1-4, LOXL1-4, LOXL1 |
| Related Diseases | Als, ALS |
| Related Pathways | LOX/LOXL1-4 Family, Lipid Metabolism, Immune Response |
graph TD
LR_LOXL3["LR.LOXL3"]
LR_LOXL3 -->|"expressed in"| Endostyle["Endostyle"]
LR_LOXL3 -->|"expressed in"| Liver["Liver"]
LR_LOXL3 -->|"interacts"| LOXL3["LOXL3"]
LR_LOXL3 -->|"implicated in"| Als["Als"]
LR_LOXL3 -->|"regulates"| ALS["ALS"]
LR_LOXL3 -->|"implicated in"| AND["AND"]
LR_LOXL3 -->|"implicated in"| LOX_LOXL1_4["LOX/LOXL1-4"]
LR_LOXL3 -->|"implicated in"| LOXL1_4["LOXL1-4"]
LOXL3 -->|"implicated in"| LR_LOXL3
LOX["LOX"] -->|"implicated in"| LR_LOXL3
LOXL1["LOXL1"] -->|"implicated in"| LR_LOXL3
LOXL1_4 -->|"regulates"| LR_LOXL3
AND -->|"regulates"| LR_LOXL3
LOX_LOXL1_4 -->|"regulates"| LR_LOXL3| Target | Relation | Type | Str |
|---|---|---|---|
| Endostyle | expressed_in | cell_type | 0.93 |
| Liver | expressed_in | cell_type | 0.93 |
| LOX/LOXL1-4 Family | associated_with | pathway | 0.90 |
| LOXL3 | interacts_with | gene | 0.85 |
| Als | implicated_in | disease | 0.65 |
| ALS | regulates | disease | 0.65 |
| AND | implicated_in | gene | 0.60 |
| LOX/LOXL1-4 | implicated_in | gene | 0.60 |
| LOXL1-4 | implicated_in | gene | 0.60 |
| Lipid Metabolism | implicated_in | pathway | 0.60 |
| Immune Response | implicated_in | pathway | 0.60 |
| LOXL1 | regulates | gene | 0.60 |
| Immune Response | regulates | pathway | 0.60 |
| Lipid Metabolism | regulates | pathway | 0.60 |
| LOXL3 | regulates | gene | 0.60 |
| LOXL1-4 | regulates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
| LOX | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||