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Mechanism: BIN1→Endosomal Dysfunction→Tau Pathology→AD Causal Chain
mechanism
1,896 words
KG: ent-gene-e9e639fd
Contents
BIN1→Endosomal Dysfunction→Tau Pathology→AD Causal Chain
🔬
Protein Info
Gene Symbol
ent-gene-e9e639fd
KG Connections
10
knowledge graph edges
Databases
GeneCards
UniProt
NCBI Gene
HPA
STRING
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Knowledge Graph
Agent Input
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🌐 Cross-references
Wikipedia
Related Hypotheses (22)
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Brain Insulin Resistance with Glucose Transporter Dysfunctio
Score: 0.60
← Prev
pg 2/2
Related Analyses (30)
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Microglia-astrocyte crosstalk amplification loops in neurode
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Autophagy-lysosome pathway convergence across neurodegenerat
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Show 25 more
Related Experiments (9)
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clinical · proposed · Score: 0.40
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validation · proposed · Score: 0.45
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clinical · proposed · Score: 0.40
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clinical · proposed · Score: 0.40
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clinical · proposed · Score: 0.40
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clinical · proposed · Score: 0.40
Show 4 more
Knowledge Graph (10 edges)
29479533
binds to
ent-gene-e9e639fd
29479533
interacts with
ent-gene-e9e639fd
29479533
is the second most significant risk factor for
ent-gene-e9e639fd
29479533
has been shown to interact with
ent-gene-e9e639fd
29479533
is not expressed by
ent-gene-e9e639fd
29479533
is expressed in
ent-gene-e9e639fd
29479533
is predominantly expressed in
ent-gene-e9e639fd
29479533
is expressed by
ent-gene-e9e639fd
ent-gene-e9e639fd
has_risk_variant
rs6733839
ent-gene-e9e639fd
participates_in_pathway
R-HSA-8856828
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