protein 1,791 words KG: ALSINPROTEIN 2026-03-24
kind:proteinsection:proteinsstate:publishedevidence:strong
Contents

Alsin Protein

🔬 Protein Info
Gene SymbolALSIN
Full NameAlsin
AliasesALS2/Alsin
Chromosome2q33.
Protein TypeGene
FunctionAlsin is a multiunctional protein with several key cellular roles:
Subcellular Localizationthe cytoplasm and associated with endosomal membranes, where it regulates the fusion and movement of early endosomes thr
Molecular Weight210 kDa
Amino Acids847 aa
UniProt IDSearch UniProt
GeneCardsALSIN
Human Protein AtlasALSIN
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Glaucoma
KG Connections19 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (4)

R-Loop Resolution Enhancement Therapy
Score: 0.43
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (22)

s:** - Single-cell RNA-seq to measure editing efficiency acr
falsification · proposed · Score: 0.40
Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40
ALS Progression Rate Heterogeneity — mechanism and biomarker
clinical · proposed · Score: 0.40
ALS Regional Onset and Spread: Network-Level Staging Model
clinical · proposed · Score: 0.40
Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in